[{"@context":"https:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/www.rizklaw.com\/blog\/drug-gives-new-hope-to-traumatic-brain-injury-patients\/#BlogPosting","mainEntityOfPage":"https:\/\/www.rizklaw.com\/blog\/drug-gives-new-hope-to-traumatic-brain-injury-patients\/","headline":"New Hope for Traumatic Brain Injury Patients","name":"New Hope for Traumatic Brain Injury Patients","description":"A drug commonly used to treat depression and\u00a0schizophrenia now shows promise in restoring memory to patients with traumatic brain syndrome. Tetra Discovery\u00a0(a pharmaceutical company in Boston), in association with the\u00a0University of Miami\u00a0Miller School of Medicine, Department of Neurological Surgery, and funded by the\u00a0National Institutes of Health (NIH\/NINDS), has found that a certain\u00a0phosphodiesterase-4 inhibitor (PDE4B)\u00a0has the...","datePublished":"2016-10-09","dateModified":"2024-05-02","author":{"@type":"Person","@id":"https:\/\/www.rizklaw.com\/blog\/author\/rizklaw\/#Person","name":"Rizk Law","url":"https:\/\/www.rizklaw.com\/blog\/author\/rizklaw\/","identifier":9,"image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/10e23ce5e6c4dadb4589cd8edf2c3f59ac356a6e876c3656917777913d9c3bc1?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/10e23ce5e6c4dadb4589cd8edf2c3f59ac356a6e876c3656917777913d9c3bc1?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Rizk Law","logo":{"@type":"ImageObject","@id":"https:\/\/www.rizklaw.com\/wp-content\/uploads\/2024\/03\/rizk-law-logo-footer.jpg","url":"https:\/\/www.rizklaw.com\/wp-content\/uploads\/2024\/03\/rizk-law-logo-footer.jpg","width":278,"height":65}},"image":{"@type":"ImageObject","@id":"https:\/\/www.rizklaw.com\/wp-content\/uploads\/2024\/03\/Richard-Rizk-headshot.jpg","url":"https:\/\/www.rizklaw.com\/wp-content\/uploads\/2024\/03\/Richard-Rizk-headshot.jpg","width":383,"height":427},"url":"https:\/\/www.rizklaw.com\/blog\/drug-gives-new-hope-to-traumatic-brain-injury-patients\/","about":["Personal Injury"],"wordCount":370,"articleBody":"A drug commonly used to treat depression and\u00a0schizophrenia now shows promise in restoring memory to patients with traumatic brain syndrome.Tetra Discovery\u00a0(a pharmaceutical company in Boston), in association with the\u00a0University of Miami\u00a0Miller School of Medicine, Department of Neurological Surgery, and funded by the\u00a0National Institutes of Health (NIH\/NINDS), has found that a certain\u00a0phosphodiesterase-4 inhibitor (PDE4B)\u00a0has the ability to bring memory back to those suffering from the effects of a traumatic brain injury (TBI).Learning and Memory Difficulties with TBITraumatic brain injury is caused by a violent blow or jolt to the head or body, with or without skull penetration, which causes mild to long-term dysfunction of brain cells. Nearly eight out of ten TBI survivors from a brain injury experience learning and memory difficulties months to years after a brain trauma.According to the CDC (United States Centers for Disease Control and Prevention),\u00a0approximately 1.5 million people in the U.S. suffer\u00a0from\u00a0a traumatic brain injury\u00a0each year, and more than 5.3 million people\u00a0live with disabilities\u00a0caused by\u00a0TBI. So far, the most successful treatments have been with either Ritalin or Aricept, but neither has been shown to improve memory.Central Nervous System Chemical Shows Promise in Treating TBIPDE4Bs, known to improve memory and wakefulness in central nervous system disorders such as clinical depression, anxiety disorders, schizophrenia, Parkinson\u2019s disease, and Alzheimer\u2019s disease, now shows ability to restore memory to those suffering from TBI.Research studies have shown that brain trauma inhibits a protein in nerve cells that is critical for memory. Researchers have now found that treatment of traumatized brains of rats with a certain kind of PDE4B inhibitor significantly reverses TBI-induced memory loss. The goal of the researchers with these studies has been to restore the learning and memory performance of TBI animals to nearly non-injury levels.Research to Continue with Human TBI SurvivorsThe joint research project is an example of collaboration between academic researchers studying animal models of brain injury and a biotech company with expertise in human clinical trials. The University of Miami plans to continue its collaboration with Tetra with a clinical trial using this therapeutic strategy with human TBI survivors."},{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Blog","item":"https:\/\/www.rizklaw.com\/blog\/#breadcrumbitem"},{"@type":"ListItem","position":2,"name":"New Hope for Traumatic Brain Injury Patients","item":"https:\/\/www.rizklaw.com\/blog\/drug-gives-new-hope-to-traumatic-brain-injury-patients\/#breadcrumbitem"}]}]